Possible Bacterial Trigger for MS & Other News of Note

Multiple Sclerosis May Be Triggered by Factors from Common Human Bacteria (Medical News Today)

Current research suggests that a common oral bacterium may exacerbate autoimmune disease. The related report by Nichols et al, “Unique Lipids from a Common Human Bacterium Represent a New Class of TLR2 Ligands Capable of Enhancing Autoimmunity,” appears in the December 2009 issue of The American Journal of Pathology.

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Porphyromas gingivalis, a common oral bacterium in humans, produces a unique type of lipid, phosphorylated dihydroceramides (DHCs), which enhance inflammatory responses. These lipids are also likely produced by bacteria found in other parts of the body including the gastrointestinal tract. To determine if these lipids accentuate immune-mediated damage in autoimmune disease, researchers led by Robert B. Clark and Frank C. Nichols of the University of Connecticut Health Center administered phosphorylated DHCs in a mouse model of MS. The severity of disease was significantly enhanced by the addition of these lipids in a manner that was dependent on activation of the immune system. These data suggest that phosphorylated DHCs from bacteria commonly found in humans may trigger or increase the severity of autoimmune diseases such as multiple sclerosis…More

Study Questions Safety of Mammograms for Young Women at High Risk of Cancer (NY Times)

For young women who have a high risk of breast cancer because of genetic mutations or family history, the radiation from yearly mammograms may make the risk even higher, researchers reported at a radiology conference on Monday.

The report is particularly troubling because it suggests that the very women who are told they need mammograms most may also be the most vulnerable to harm from them. Doctors routinely urge high-risk women to have mammograms earlier in life and more often than women judged to be at average risk.

Researchers caution that the new report is not conclusive, and that the issue needs more study…More

Tests Find More than 200 Chemicals in Newborn Umbilical Cord Blood (Scientific American)

U.S. minority infants are born carrying hundreds of chemicals in their bodies, according to a report released today by an environmental group.

The Environmental Working Group’s study commissioned five laboratories to examine the umbilical cord blood of 10 babies of African-American, Hispanic and Asian heritage and found more than 200 chemicals in each newborn.

“We know the developing fetus is one of the most vulnerable populations, if not the most vulnerable, to environmental exposure,” said Anila Jacobs, EWG senior scientist. “Their organ systems aren’t mature and their detox methods are not in place, so cord blood gives us a good picture of exposure during this most vulnerable time of life”…More

Western Diets Turn on Fat Genes (PhysOrg)

Those extra helpings of gravy and dessert at the holiday table are even less of a help to your waistline than previously thought. According to a new research report recently appearing online in The FASEB Journal, a diet that is high in fat and in sugar actually switches on genes that ultimately cause our bodies to store too much fat. This means these foods hit you with a double-whammy as the already difficult task of converting high-fat and high-sugar foods to energy is made even harder because these foods also turn our bodies into “supersized fat-storing” machines…More

Can Cleft Palate Be Healed Before Birth? (PhysOrg)

In a study newly published in the journal Development, investigators at the USC School of Dentistry describe how to non-surgically reverse the onset of cleft palate in fetal mice – potentially one step in the journey to a better understanding of similar defects in humans…More

 

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About The Verigin Dental Health Team

A humanistic, holistic dental practice in Northern California, providing integrative, biological, mercury-free dentistry
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