Cancer & Hormone Therapy, & Other News of Note

Breast Cancer Seen as Riskier with Hormone (NY Times)

Hormone treatment after menopause, already known to increase the risk of breast cancer, also makes it more likely that the cancer will be advanced and deadly, a study finds.

Women who took hormones and developed breast cancer were more likely to have cancerous lymph nodes, a sign of more advanced disease, and were more likely to die from the disease than were breast cancer patients who had never taken hormones…More

Eating Mostly Whole Grains, Few Refined Grains Linked to Lower Body Fat (ScienceDaily)

People who consume several servings of whole grains per day while limiting daily intake of refined grains appear to have less of a type of fat tissue thought to play a key role in triggering cardiovascular disease and type 2 diabetes, a new study suggests.

Researchers at the Jean Mayer USDA Human Nutrition Researcher Center on Aging (USDA HNRCA) at Tufts University observed lower volumes of Visceral Adipose Tissue (VAT) in people who chose to eat mostly whole grains instead of refined grains.

“VAT volume was approximately 10 % lower in adults who reported eating three or more daily servings of whole grains and who limited their intake of refined grains to less than one serving per day,” says first author Nicola McKeown, PhD, a scientist with the Nutritional Epidemiology Program at the USDA HNRCA…More

Junk Food Nearly Half of Kids’ Calorie Intake (ABC News)

If there were ever a reason to cut back on kids’ consumption of cake, cookies, pizza and soda, nutrition experts say a new study highlights just how unhealthy young people’s diets really are.

Researchers from the National Cancer Institute in Bethesda, Md. analyzed data from the National Health and Nutrition Examination Survey and found that nearly 40 percent of calories consumed by children ages 2 to 18 were empty calories, the unhealthiest kind of calories.

Half of these calories came from just six foods: Soda; sugary fruit drinks; grain desserts, such as cake, cookies and donuts; dairy desserts such as ice cream; pizza; [and] whole milk, which is far fattier than skim…More

Western Diet Exacerbates Sepsis (PhysOrg)

High fat diets cause a dramatic immune system overreaction to sepsis, a condition of systemic bacterial infection. An experimental study in mice, published in the open access journal BMC Physiology, has shown that a diet high in saturated fat, sugars and cholesterol greatly exaggerates the inflammatory response to sepsis.

Chantal Rivera, PhD Associate Professor of Molecular and Cellular Physiology at Louisiana State University Health Sciences Center-Shreveport, said that “Mortality due to sepsis in morbidly obese subjects is estimated to be 7 times more prevalent compared to mortality in lean individuals. Morbidity in obese patients is also more severe. Results from our recent studies suggest that this adverse outcome may be caused by consuming a high-fat diet, which predisposes the immune system to react more strongly to infection”…More

No Standard for the Placebo? (ScienceDaily)

Much of medicine is based on what is considered the strongest possible evidence: The placebo-controlled trial. A paper published in the October 19 issue of Annals of Internal Medicine entitled “What’s In Placebos: Who Knows?” calls into question this foundation upon which much of medicine rests, by showing that there is no standard behind the standard – no standard for the placebo.

The thinking behind relying on placebo-controlled trials is this: to be sure a treatment itself is effective, one needs to compare people whose only difference is whether or not they are taking the drug. Both groups should equally think they are on the drug – to protect against effects of factors like expectation. So study participants are allocated “randomly” to the drug or a “placebo” – a pill that might be mistaken for the active drug but is inert.

But, according to the paper’s author, Beatrice Golomb, MD, PhD, associate professor of medicine at the University of California, San Diego School of Medicine, this standard has a fundamental problem: “There isn’t anything actually known to be physiologically inert. On top of that, there are no regulations about what goes into placebos, and what is in them is often determined by the makers of the drug being studied, who have a vested interest in the outcome. And there has been no expectation that placebos’ composition be disclosed. At least then readers of the study might make up their own mind about whether the ingredients in the placebo might affect the interpretation of the study”…More

 

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Published by The Verigin Dental Health Team

A humanistic, holistic dental practice in Northern California, providing integrative, biological, mercury-free dentistry

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